ACTIVATED PROTEIN C (APC) RESISTANCE IN INDIAN CHILDREN WITH THROMBOEMBOLISM

Activated protein C (APC) resistance in young stroke patients.

Physiological anticoagulation. Resistance to activated protein C and venous thromboembolism.

Impact of progestagens on activated protein C (APC) resistance among users of oral contraceptives.

Oral contraceptive (OC) use is associated with an increased risk of venous thromboembolism. Previous data reported higher thrombotic risk in women using third-generation combined OC than in those using second generation OC. The difference could be explained by differential effects of progestagens on plasma sensitivity to activated protein C (APC). The main purpose of this cross-sectional study ...

Inherited thrombophilia: resistance to activated protein C as a pathogenic factor of venous thromboembolism.

V ENOUS THROMBOEMBOLISM, with an annual incidence of 1/1,000, is a serious medical problem causing considerable suffering and occasional death.‘-3 Thrombosis tends to occur in conjunction with surgery, fractures, inflammatory states, immobilization, pregnancy, and the use of oral contraceptives, demonstrating circumstantial risk factors to be of importance in the pathogenesis. In addition, thro...

Activated protein C resistance: the most common risk factor for venous thromboembolism.

BACKGROUND Venous thromboembolism is a major cause of morbidity and mortality. Although activated protein C resistance (APC-R) is the most commonly recognized inherited risk factor for venous thromboembolism, little is known about its long-term implications on health. METHODS MEDLINE was searched from January 1989 through August 1999 using the key words "thromboembolism," "thrombosis," "activ...